AQT0794 PhosphoSens® Tyrosine Kinase Substrate
A PhosphoSens® tyrosine kinase substrate validated for 67 kinases (46 wild-type, 21 mutant), including SRC, ALK, FGFR1. Continuous, direct, real-time activity measurement — no antibodies, no coupling enzymes, no radioactivity.
- Catalog number
- AQT0794
- Enzyme class
- Kinase
- Residue specificity
- Tyrosine
- Validated kinases
- 67
- Assay formats
- Kinetic · 67
- Kinase families
- 16
Kinases validated with AQT0794
Every kinase below has a validated PhosphoSens® assay using AQT0794. Select a target to see its kits, recombinant enzyme, pricing and protocols.
| Kinase | Type | Family | Format with AQT0794 | Link |
|---|---|---|---|---|
| ALK | Wild-type | ALK | Kinetic | View assay → |
| ALK [G1202R] | Mutant | ALK | Kinetic | View assay → |
| ALK [I1171N/D1203N] | Mutant | ALK | Kinetic | View assay → |
| ALK [L1196M/G1202R] | Mutant | ALK | Kinetic | View assay → |
| AXL | Wild-type | Axl | Kinetic | View assay → |
| BLK | Wild-type | Src | Kinetic | View assay → |
| BMX | Wild-type | Tec | Kinetic | View assay → |
| CSF1R | Wild-type | PDGFR | Kinetic | View assay → |
| CSK | Wild-type | Csk | Kinetic | View assay → |
| ERBB2 | Wild-type | EGFR | Kinetic | View assay → |
| ERBB2 (HER2) [780_781insGSP] | Mutant | EGFR | Kinetic | View assay → |
| ERBB2 (HER2) [D769H] | Mutant | EGFR | Kinetic | View assay → |
| ERBB2 (HER2) [D769Y] | Mutant | EGFR | Kinetic | View assay → |
| ERBB2 (HER2) [G776VC] | Mutant | EGFR | Kinetic | View assay → |
| ERBB2 (HER2) [V777_G778insCG] | Mutant | EGFR | Kinetic | View assay → |
| ERBB2 (HER2) [V777L] | Mutant | EGFR | Kinetic | View assay → |
| ERBB2 [A775/G776insYVMA] | Mutant | EGFR | Kinetic | View assay → |
| ERBB4 | Wild-type | EGFR | Kinetic | View assay → |
| ERBB4 (HER4) [R927Q] | Mutant | EGFR | Kinetic | View assay → |
| FER | Wild-type | Fer | Kinetic | View assay → |
| FES | Wild-type | Fer | Kinetic | View assay → |
| FGFR1 | Wild-type | FGFR | Kinetic | View assay → |
| FGFR2 | Wild-type | FGFR | Kinetic | View assay → |
| FGFR2 [C491A V564L] | Mutant | FGFR | Kinetic | View assay → |
| FGFR2 [V564F] | Mutant | FGFR | Kinetic | View assay → |
| FGFR3 | Wild-type | FGFR | Kinetic | View assay → |
| FGFR3 [V555M] | Mutant | FGFR | Kinetic | View assay → |
| FGFR4 | Wild-type | FGFR | Kinetic | View assay → |
| FLT1 | Wild-type | VEGFR | Kinetic | View assay → |
| FLT3 | Wild-type | PDGFR | Kinetic | View assay → |
| FLT4 | Wild-type | VEGFR | Kinetic | View assay → |
| FRK | Wild-type | Src | Kinetic | View assay → |
| FYN (FYNa) | Wild-type | Src | Kinetic | View assay → |
| FYN (FYNb) | Wild-type | Src | Kinetic | View assay → |
| HCK | Wild-type | Src | Kinetic | View assay → |
| IGF1R | Wild-type | InsR | Kinetic | View assay → |
| INSR | Wild-type | InsR | Kinetic | View assay → |
| KDR | Wild-type | VEGFR | Kinetic | View assay → |
| LCK | Wild-type | Src | Kinetic | View assay → |
| LTK | Wild-type | ALK | Kinetic | View assay → |
| LYN (LYNa) | Wild-type | Src | Kinetic | View assay → |
| LYN (LYNb) | Wild-type | Src | Kinetic | View assay → |
| MATK | Wild-type | Csk | Kinetic | View assay → |
| MERTK | Wild-type | Axl | Kinetic | View assay → |
| MST1R | Wild-type | Met | Kinetic | View assay → |
| NTRK1 | Wild-type | Trk | Kinetic | View assay → |
| NTRK2 | Wild-type | Trk | Kinetic | View assay → |
| NTRK3 | Wild-type | Trk | Kinetic | View assay → |
| NTRK3 [G623E] | Mutant | Trk | Kinetic | View assay → |
| NTRK3 [G623R] | Mutant | Trk | Kinetic | View assay → |
| NTRK3 [G696A] | Mutant | Trk | Kinetic | View assay → |
| PTK6 | Wild-type | Src | Kinetic | View assay → |
| SRC | Wild-type | Src | Kinetic | View assay → |
| SRC N1 | Wild-type | Src | Kinetic | View assay → |
| SRMS | Wild-type | Src | Kinetic | View assay → |
| SYK | Wild-type | Syk | Kinetic | View assay → |
| TEC | Wild-type | Tec | Kinetic | View assay → |
| TEK | Wild-type | Tie | Kinetic | View assay → |
| TEK [A1124V] | Mutant | Tie | Kinetic | View assay → |
| TEK [L914F] | Mutant | Tie | Kinetic | View assay → |
| TEK [P883A] | Mutant | Tie | Kinetic | View assay → |
| TEK [Y897S] | Mutant | Tie | Kinetic | View assay → |
| TNK1 | Wild-type | Ack | Kinetic | View assay → |
| TXK | Wild-type | Tec | Kinetic | View assay → |
| TYRO3 | Wild-type | Axl | Kinetic | View assay → |
| YES1 | Wild-type | Src | Kinetic | View assay → |
| ZAP70 | Wild-type | Syk | Kinetic | View assay → |
No kinases match that search.
Bulk substrate
AQT0794 PhosphoSens® Kinase Substrate
Bulk substrate for assay development, screening and high-throughput workflows. Kinase assay kits that include AQT0794 are on each target's assay page.
How PhosphoSens® substrates work
PhosphoSens® substrates are peptides carrying an environment-sensitive fluorophore next to the phospho-acceptor residue. When the kinase transfers a phosphate to the substrate, fluorescence increases, so activity is read continuously and directly in a plate reader.
- Real-time progress curves, not single end-points
- Run at physiologically relevant ATP concentrations
- No antibodies, coupling enzymes, wash steps or radioactivity
- One substrate across 67 kinases simplifies selectivity and panel work
Frequently asked questions
Which kinases is AQT0794 validated for?
AQT0794 is validated for 67 kinases (46 wild-type and 21 mutant), including SRC, ALK, FGFR1. See the full list above.
Which PhosphoSens assay formats use AQT0794?
AQT0794 is the PhosphoSens-Kinetic substrate for 67 kinases.
What sizes is AQT0794 available in?
1 mg, 5 mg, 10 mg and 20 mg, priced from $2795 (1 mg) to $37285 (20 mg) USD.