Validated Phosphatase Activity Assays for Drug Discovery
Explore biochemical phosphatase assays designed to quantify enzymatic activity with confidence across discovery and lead optimization.
PhosphoSens® phosphatase assays provide direct, substrate-level measurement of phosphatase activity in a simple, homogeneous workflow — enabling reliable profiling of inhibitors, mechanism of action, and selectivity.
- • Direct measurement of phosphatase activity at the substrate level
• Continuous kinetic and TRF endpoint formats
• Optimized for physiologically relevant cofactors and buffer conditions
• Compatible with hit validation, IC₅₀, selectivity, and MOA studies
What’s Included in the Phosphatase Assay Catalog
This catalog lists validated phosphatase targets for which AssayQuant offers PhosphoSens® activity assays, substrates, and supporting reagents.
Each target page provides:
- Available PhosphoSens®-Kinetic and PhosphoSens®-Red assay formats
- Ready-to-use assay kits and bulk substrates
- Compatible recombinant phosphatases and variants
- Application guidance for screening, profiling, and mechanistic studies
Search by gene symbol, target name, or keyword to quickly locate validated phosphatase assays and click any target to view available formats, substrates, enzymes, and pricing options.
| Target | Full Name | View |
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Why Researchers Choose PhosphoSens® Phosphatase Assays
Unlike antibody-based or endpoint-only approaches, PhosphoSens® assays directly measure enzymatic activity at the substrate level — delivering clear, interpretable data for phosphatase biology and inhibitor characterization.
PhosphoSens® assays generate reproducible activity measurements across a range of phosphatase classes, supporting confident decision-making from early screening through lead optimization.
Understand How Our Technology Can Support Your Next Discovery
Deep Kinetic Characterization: When IC50 Isn't Enough
A continuous assay, like our PhosphoSens assay, that measures the catalytic event of phosphorylation in real time enables determination of kinetic parameters that power your drug discovery research.
Continuous vs. Endpoint Kinase Assays: What You Need to Know
PhosphoSens-Kinetic Phosphatase Inhibitor IC50 Determination
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