Custom Assay Development

Addressing Your Unique Kinase & Phosphatase Target Needs

AssayQuant Technologies is continually developing new assays to expand coverage and meet the rapidly changing needs of the marketplace. If we don't have your specific kinase or phosphatase assay, we can custom develop a validated assay to meet your needs.

Highly Predictable Process

Custom assay development typically takes 4-8 weeks per milestone and can stop at any time once your needs are met. Our typical development process is:

  • Milestone 1 – Screening of subsets of our 30,000+ CSox-based sensor substrate sequences. 
  • Milestone 2 – Optimization of the best substrate sequence identified in Milestone 1. Synthesize and test single substitutions at each position with 16 amino acids.
  • Milestone 3 – Synthesize and test combinations of favorable substitutions identified in Milestone 2 to identify minimum change that maximizes assay performance.
  • Milestone 4 & 5 – Perform additional CSox-peptide Library optimization to improve selectivity for analysis of activity in Crude Lysates.

Older Omnia versus Newer PhosphoSens (RDF or CSox) Technology format

If you previously used an Omnia Kinase Assay, we can provide any of these Sox-based substrates. Moreover, in most cases, we have improved substrates using the Recognition Domain Focused (RDF) or CSox technology that provide superior performance. Please inquire to find out how we can provide you with a seamless transition that enables your efforts.

Older Omnia versus Newer PhosphoSens

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