Substrates and
Reagents
Kinome Profiling Services
Compound Testing Services
Activity-based Sensor Peptides for Direct, High-throughput, and Kinetic Quantitation of Oncogenic Protein Kinases in Unfractionated Cell and Tissue Samples
AssayQuant Technologies was awarded an SBIR Direct Phase II grant on August 15, 2024, to expand PhosphoSens® fluorescence-peptide detection technology for measuring kinase activity in complex samples like cell lysates. This innovation addresses critical gaps in current assay methods, providing a user-friendly, high-impact solution for kinase research and drug development.
Sox-based Sensor Phosphopeptides for Continuous, Homogeneous, and Quantitative Monitoring of Protein Phosphatase Activity
Protein phosphatases are critical drug targets for cancer therapy development with a need for robust assays that monitor phosphatase enzyme activity. Learn how our assays continuously monitor protein phosphatase activity.
The Advantages of Kinome Profiling With a Continuous Assay
Join Earl May, Ph.D., Sr. Director of Discovery Technologies, as he delves into the unique advantages of continuous assays over their endpoint counterparts, reveals hidden insights within raw data, and demonstrates how progress curves can help you identify essential aspects of an inhibitor's mode of action.
Development of a Real-Time, Fluorescence Microplate Assay for Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Activity
Epidermal Growth Factor Receptor (EGFR) wild-type and mutant tyrosine kinase activity and the downstream signaling cascades are pivotal in oncogenesis, drug resistance, and tumor recurrence. Learn how our team developed a continuous, real-time, fluorescence-based assay for EGFR tyrosine kinase inhibitors (TKI’s).
