AQT0653 PhosphoSens® Tyrosine Kinase Substrate
A PhosphoSens® tyrosine kinase substrate validated for 32 kinases, including EGFR, SRC, JAK1 (JH1). Continuous, direct, real-time activity measurement — no antibodies, no coupling enzymes, no radioactivity.
- Catalog number
- AQT0653
- Enzyme class
- Kinase
- Residue specificity
- Tyrosine
- Validated kinases
- 32
- Assay formats
- Red · 32
- Kinase families
- 15
Kinases validated with AQT0653
Every kinase below has a validated PhosphoSens® assay using AQT0653. Select a target to see its kits, recombinant enzyme, pricing and protocols.
| Kinase | Type | Family | Format with AQT0653 | Link |
|---|---|---|---|---|
| ALK | Wild-type | ALK | Red | View assay → |
| AXL | Wild-type | Axl | Red | View assay → |
| CSF1R | Wild-type | PDGFR | Red | View assay → |
| CSK | Wild-type | Csk | Red | View assay → |
| EGFR | Wild-type | EGFR | Red | View assay → |
| EPHA2 | Wild-type | Eph | Red | View assay → |
| EPHA6 | Wild-type | Eph | Red | View assay → |
| EPHA7 | Wild-type | Eph | Red | View assay → |
| EPHA8 | Wild-type | Eph | Red | View assay → |
| FLT1 | Wild-type | VEGFR | Red | View assay → |
| FLT4 | Wild-type | VEGFR | Red | View assay → |
| FRK | Wild-type | Src | Red | View assay → |
| INSRR | Wild-type | InsR | Red | View assay → |
| JAK1 (JH1) | Wild-type | Jak | Red | View assay → |
| JAK1 (JH1JH2) | Wild-type | Jak | Red | View assay → |
| JAK2 (JH1) | Wild-type | Jak | Red | View assay → |
| JAK2 (JH1JH2) | Wild-type | Jak | Red | View assay → |
| JAK3 (JH1) | Wild-type | Jak | Red | View assay → |
| KDR | Wild-type | VEGFR | Red | View assay → |
| LTK | Wild-type | ALK | Red | View assay → |
| LYN (LYNb) | Wild-type | Src | Red | View assay → |
| MST1R | Wild-type | Met | Red | View assay → |
| PDGFRA | Wild-type | PDGFR | Red | View assay → |
| PTK2 | Wild-type | FAK | Red | View assay → |
| PTK6 | Wild-type | Src | Red | View assay → |
| SRC | Wild-type | Src | Red | View assay → |
| SRMS | Wild-type | Src | Red | View assay → |
| SYK | Wild-type | Syk | Red | View assay → |
| TEC | Wild-type | Tec | Red | View assay → |
| TEK | Wild-type | Tie | Red | View assay → |
| TXK | Wild-type | Tec | Red | View assay → |
| ZAP70 | Wild-type | Syk | Red | View assay → |
No kinases match that search.
Bulk substrate
AQT0653 PhosphoSens® Kinase Substrate
Bulk substrate for assay development, screening and high-throughput workflows. Kinase assay kits that include AQT0653 are on each target's assay page.
How PhosphoSens® substrates work
PhosphoSens® substrates are peptides carrying an environment-sensitive fluorophore next to the phospho-acceptor residue. When the kinase transfers a phosphate to the substrate, fluorescence increases, so activity is read continuously and directly in a plate reader.
- Real-time progress curves, not single end-points
- Run at physiologically relevant ATP concentrations
- No antibodies, coupling enzymes, wash steps or radioactivity
- One substrate across 32 kinases simplifies selectivity and panel work
Frequently asked questions
Which kinases is AQT0653 validated for?
AQT0653 is validated for 32 kinases, including EGFR, SRC, JAK1 (JH1). See the full list above.
Which PhosphoSens assay formats use AQT0653?
It is the PhosphoSens-Red substrate for 32 kinases.
What sizes is AQT0653 available in?
1 mg, 5 mg, 10 mg and 20 mg, priced from $2795 (1 mg) to $37285 (20 mg) USD.