A twist in the tale: shifting from covalent targeting of a tyrosine in JAK3 to a lysine in MK2

Hillebrand L, Wang G, Rasch A, … Gehringer M · RSC Med Chem 2025 · RSC Med Chem 16(10):4906-4919

JAK3, MK2 Tyrosine kinase Covalent inhibitor kineticsInhibitor discovery & SARMechanism & structural biology PhosphoSens