AQT0032 PhosphoSens® Tyrosine Kinase Substrate
A PhosphoSens® tyrosine kinase substrate validated for 11 kinases (2 wild-type, 9 mutant), including ABL1, ABL2. Continuous, direct, real-time activity measurement — no antibodies, no coupling enzymes, no radioactivity.
- Catalog number
- AQT0032
- Enzyme class
- Kinase
- Residue specificity
- Tyrosine
- Validated kinases
- 11
- Assay formats
- Kinetic · 11
- Kinase families
- 2
Kinases validated with AQT0032
Every kinase below has a validated PhosphoSens® assay using AQT0032. Select a target to see its kits, recombinant enzyme, pricing and protocols.
| Kinase | Type | Family | Format with AQT0032 | Link |
|---|---|---|---|---|
| ABL1 | Wild-type | Abl | Kinetic | View assay → |
| ABL1 [E255K] | Mutant | Abl | Kinetic | View assay → |
| ABL1 [E255V] | Mutant | Abl | Kinetic | View assay → |
| ABL1 [H396P] | Mutant | Abl | Kinetic | View assay → |
| ABL1 [Q252H] | Mutant | Abl | Kinetic | View assay → |
| ABL1 [T315I] | Mutant | Abl | Kinetic | View assay → |
| ABL1 [Y245F/Y412F] | Mutant | ABL | Kinetic | View assay → |
| ABL1 [Y245F] | Mutant | ABL | Kinetic | View assay → |
| ABL1 [Y253F] | Mutant | Abl | Kinetic | View assay → |
| ABL1 [Y253H] | Mutant | Abl | Kinetic | View assay → |
| ABL2 | Wild-type | Abl | Kinetic | View assay → |
No kinases match that search.
Bulk substrate
AQT0032 PhosphoSens® Kinase Substrate
Bulk substrate for assay development, screening and high-throughput workflows. Kinase assay kits that include AQT0032 are on each target's assay page.
How PhosphoSens® substrates work
PhosphoSens® substrates are peptides carrying an environment-sensitive fluorophore next to the phospho-acceptor residue. When the kinase transfers a phosphate to the substrate, fluorescence increases, so activity is read continuously and directly in a plate reader.
- Real-time progress curves, not single end-points
- Run at physiologically relevant ATP concentrations
- No antibodies, coupling enzymes, wash steps or radioactivity
- One substrate across 11 kinases simplifies selectivity and panel work
Frequently asked questions
Which kinases is AQT0032 validated for?
AQT0032 is validated for 11 kinases (2 wild-type and 9 mutant), including ABL1, ABL2. See the full list above.
Which PhosphoSens assay formats use AQT0032?
AQT0032 is the PhosphoSens-Kinetic substrate for 11 kinases.
What sizes is AQT0032 available in?
1 mg, 5 mg, 10 mg and 20 mg, priced from $2795 (1 mg) to $37285 (20 mg) USD.