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First Selective Small Molecule Inhibitor of FGFR4 for the Treatment of Hepatocellular Carcinomas with an Activated FGFR4 Signaling Pathway

Hagel M, Miduturu C, Sheets M, … Guzi T · Cancer Discov 2015 · Cancer Discov 5(4):424-37

FGFR4 (Tyr), Covalent Inhibitors Tyrosine kinase Covalent inhibitor kineticsInhibitor discovery & SARSelectivity & kinome profiling PhosphoSens

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