WHO WE ARE

We help scientists find better drugs, faster.

AssayQuant Technologies was founded by MIT scientists who believed there had to be a better way to study kinases and phosphatases — the enzymes at the heart of most disease biology and a huge proportion of drug targets.

Traditional assay tools were slow, indirect, and prone to false signals. So we built something different: real-time, continuous enzyme activity assays that give researchers a direct, moment-by-moment view of what's happening in their samples.

Today, we're a team of scientists, engineers, and drug discovery veterans working together to make that technology accessible to researchers everywhere — from academic labs to the world's largest pharma companies.

0

Validated Enzyme Targets

0

Peptide Sequences

0

Peer-Reviewed Publications

0

Years of Innovation

WHAT WE DO

Delivering Real-Time Insights Into Enzyme Activity

We develop and commercialize continuous enzyme activity assays powered by our patented PhosphoSens® Technology. Instead of giving you a single endpoint snapshot, our assays track substrate phosphorylation in real time — so you can see the full kinetic picture.

That means you can:

  • Understand exactly how an enzyme behaves — and how an inhibitor changes that behavior
  • Tell the difference between reversible and irreversible inhibition with confidence
  • Screen compound libraries with far fewer false positives
  • Make faster, better-informed go/no-go decisions early in discovery

Our portfolio covers kinase and phosphatase research across more than 600 targets, and supports everything from high-throughput screening to SAR profiling to mechanism-of-action studies.

INTRODUCTORY OFFER

The Best Solutions Start with a Conversation

Not sure which product or service is the best fit for your project? At AssayQuant, our team of scientific experts can provide the guidance and support you need to achieve your research goals.

 

OUR TECHNOLOGY

What makes PhosphoSens® different

Most kinase assays detect phosphorylation indirectly — using antibodies, radioactivity, or coupled enzyme reactions that add noise, complexity, and lag time. PhosphoSens® takes a fundamentally different approach.

Our fluorescent sensor peptide substrates produce a signal only when phosphorylated. No secondary reagents. No signal amplification steps. Just a clean, direct readout of enzyme activity as it happens.

We're not just selling assay kits. We work closely with research teams to design experiments, troubleshoot protocols, and make sure you're getting the most out of the platform.

OUR PEOPLE

The team behind the science

We're led by a group of people who've spent their careers at the intersection of academic discovery and real-world drug development — from MIT and Yale to Thermo Fisher, GSK, and Pfizer. That combination of depth and experience is what makes AssayQuant different from a typical tools company.

Executive Leadership Team

Bill Radany, PhD

CEO

Barbara Imperiali, PhD

Co-founder, CTO & Board Member

Erik Schaefer, PhD

Co-founder & CSO

Gerry Labonte

CFO

Earl May, PhD

Senior Director of Discovery Technologies

erik_company page

Erik Schaefer, PhD

Co-founder & CSO

Erik is co-founder and CSO of AssayQuant Technologies, Inc. He has over 25 years of experience leading innovative life science tool companies, including Promega, BioSource, Invitrogen/Life Technologies, Thermo Fisher Scientific and now AssayQuant Technologies, Inc. In his many leadership roles, Erik has built and led high-performing R&D and manufacturing teams focusing on integrating innovative technologies to enable customers across diverse market segments and drive business performance. He has developed and commercialized more than 750 new products with a focus on workflow solutions and novel assay formats to improve understanding of signal transduction pathways and phosphoregulation in normal and disease states and to enable drug development leading to more effective treatments of human disease.

Erik holds a Ph.D. in Microbiology and Molecular Genetics, with a focus on molecular and cellular biology, from the Robert Larner, M.D. College of Medicine at the University of Vermont. He has 65 peer-reviewed publications and one patent (1 pending). He did his postdoctoral studies at University of Texas Southwestern Medical Center in Dallas, TX and the Texas A&M Institute of Biosciences & Technology in Houston, TX, working on insulin receptor structure-function and creating animal models for diabetes.

Outside of AssayQuant, Erik enjoys time with his family, fly fishing, gardening and hiking.

BI-HEADSHOT_Sep24

Barbara Imperiali, PhD

Co-founder, CTO & Board Member

Barbara is co-founder and CTO of AssayQuant Technologies. She is currently the Class of 1922 Professor of Biology and Chemistry at MIT and has run an independent research group working in the fields of chemical biology and glycobiology at Carnegie Mellon, Caltech and MIT. Barbara received a B.Sc.(Hon) in Medicinal Chemistry (University College London, UK) in 1979 and a Ph.D. in Synthetic Organic Chemistry (MIT, Cambridge MA). She also carried out postdoctoral studies at MIT and Brandeis University.

Barbara’s research focuses on diverse aspects of protein structure, function and design, and she applies multi-disciplinary approaches involving organic synthesis, state-of-the-art spectroscopy, molecular modeling, enzymology, and molecular and cellular biology to address fundamental problems at the interface of chemistry and biology.

Barbara has co-authored over 220 peer-reviewed publications and 14 patents, and she is a member of the National Academy of Science.

In her free time, Barbara enjoys hiking and CrossFit and on longer escapes, she likes to go on long-distance backpacking trips.

Labonte-A

Gerry Labonte

Chief Financial Officer

Gerry is a finance and accounting executive with 30+ years of leadership experience focused on system implementation, defining roadmaps, and developing financial platforms. He has successfully led a broad range of financial implementations impacting private equity and real estate, including investment returns and calculations, and performance reporting.

Gerry’s finance and accounting experience is in diverse industries (Real estate, public accounting, consulting, etc.) for both public (State Street Bank, Brookfield Asset Management) and private (Hipercept, AEW Capital Management) companies.

He has delivered operation excellence across diverse areas, including RFP process management, accounting operations outsourcing analysis, ERP software selection and integration, large-scale implementation of accounting, finance, and warehouse management systems and automation of common financial processes to deliver improved function and efficiency.

bill_company page

Bill Radany, PhD

CEO

E. William Radany, PhD, brings over 40 years of experience in the biotechnology industry, with a strong track record of scientific innovation, executive leadership, and company building. Prior to joining AssayQuant, Dr. Radany founded the synthetic biology companies VertuBio and Verdezyne, and served as President and CEO of High Throughput Genomics, Inc., a pioneer in array-based gene expression assay technologies for the life sciences sector.

Earlier in his career, he was President of Biacore and the founding CEO of NeoGenex. Dr. Radany has also held key executive roles at leading biotech firms including Xencor, Caliper Technologies, and Stratagene, where he was instrumental in forging strategic partnerships with major pharmaceutical and biotechnology companies.

Dr. Radany earned his Bachelor of Science degree in Cell Biology from Colorado State University, and holds a Ph.D. in Biochemistry and Physiology from the University of Wyoming.

 

May-A

Earl May, PhD

Senior Director of Discovery Technologies

Earl brings over 25 years of expertise in biochemistry, biophysics, and enzymology across multiple therapeutic areas. He has held research and leadership roles for companies like SmithKline Beecham, GlaxoSmithKline, OSI Pharmaceuticals, and numerous innovative biotechnology companies. He has explored hundreds of drug targets at the early end of the pipeline and has driven dozens of projects into and through screening and hit to lead activities.

During his tenure at GlaxoSmithKline, Earl provided quantitative analysis to multiple therapeutic areas and was a part of Bob Copeland's Enzymology and Mechanistic Pharmacology group. He then moved into biotech, taking on more significant leadership roles in screening sciences and lead discovery. Over the last decade, his enzymology experience has deepened with a focus on time-dependent and irreversible inhibition, protein-protein interaction inhibitors, and three-body biophysics problems, with over half of the enzymes he targeted being kinases.

Earl received his Ph.D. in Molecular Biophysics and Biochemistry from Yale University after his undergraduate work in Biochemistry at the University of Maryland, Baltimore County. His post-doctoral work was in Nancy Craig's lab at Johns Hopkins University, where he dissected bacterial transposition in reconstituted systems.

Earl and his wife live in Watertown and have three adult children, scientists all, although one has unfortunately chosen not to use that gift.

Chin-A

Jefferson Chin

Director of Inventory Management & Automated Services (IMAS)

Jeff brings over 30 years of experience to AssayQuant within the fields of chemistry and compound management. Jeff has worked in a variety of small and large companies such as Cheminpharma, Bayer, Novartis, BMS and Pfizer. Jeff started out as a peptide chemist before transitioning to analytical chemistry, primarily NMR spectroscopy and Mass Spectrometry and finally into leadership positions within Compound Management. Jeff’s broad experience has enabled him to bring innovative ideas into compound management such as acoustic ejection mass spectrometry for the analysis of compound integrity. Jeff has co-authored over a dozen articles within the field of NMR spectroscopy and presented at SLAS conferences regarding best practices in compound management.

Jeff obtained his MBA from the University of New Haven and then decided to become an Adjunct professor within the Chemistry department teaching laboratory skills in Organic Chemistry and Instrumentation.

In his spare time, Jeff enjoys woodworking, pottery and volunteering as a mentor. Jeff is most proud of his three adult children and being able to donate a kidney to improve the quality of life.

Board of Directors

Gil Price, MD

Chairman of the Board

Barbara Imperiali, PhD

Co-founder, CTO & Board Member

Jeff Hoerle

Board Member

Karen Allen, PhD

Board Member

Albert Li

Board Member

KarenAllen

Karen Allen, PhD

Board Member

Karen is a Professor of Chemistry and the Chair of the Department of Chemistry at Boston University. Karen received a B.S. in Biology (Tufts University) in 1984 and a Ph.D. in Biochemistry (Brandeis University (Waltham, MA) in 1989. She was an American Cancer Society Post-doctoral Fellow at MIT and Brandeis University. Since 1993 she has led her own research team at Boston University, first in the Department of Physiology and Biophysics at the School of Medicine, and since 2008 in the Department of Chemistry.

Karen is a Fellow of the American Society of Biochemistry and Molecular Biology and has co-authored over 135 peer-reviewed publications. Her research is focused on the use of protein biochemistry and biophysical analysis to understand protein structure and mechanism with an eye toward therapeutics. In this context, her laboratory has plumbed the basis of enzyme-mediated phosphoryl transfer, phosphoglycosyl transfer and decarboxylation reactions.

Jeff Hoerle

Board Member

Jeff Hoerle is Managing Partner of Stone Run Capital, LLC, an investment firm based in New York.  Prior to founding SRC in 2010, Jeff worked at Reich & Tang Asset Management from 2003 as an investment analyst and portfolio manager.

Formerly, he worked at Ovid Technologies, Inc. from 1993 in a number of roles including Chief Financial Officer and Chief Operating Officer.

Mr. Hoerle has a B.A. from Yale University (1990) and an E.M.B.A. from Columbia University (1997).

Gil Price, MD

Chairman of the Board

Dr. Price is an experienced biotech executive and entrepreneur with expertise across clinical asset investment strategy, evaluation, financing and execution. Additional leadership experience within R&D, Medical, and Strategy corporate functions.

Dr. Price was previously responsible for the strategic and tactical management of all business at Drug Safety Solutions, acquired in June 2017 by Linden Capital Partners. Dr. Price now functions as the Chief Medical Consultant for the global ProPharma Group.

Over the years, Dr. Price has served on multiple corporate boards, including public, private, and not-for-profit. His board duties have included the Chairman's role on Compensation and Governance and a member's role on Audit Committee. He has served on boards that report to; TSX, NYSE American, and NASDAQ. In his recent most recent experience at Rexahn Pharmaceuticals, Inc. (NYSE American: RNN), he serves on Compensation, Governance, and Business Development Committees. In his previous role with Sarepta Therapeutics NASDAQ: SRPT, he helped guide the company's transition from an $80 million market (2008) to its current $8.4 billion market cap (2019).

Albert Li

Albert Li

Board Member

 Albert is a seasoned senior leader with over 30 years of general management, finance and business development experience in startup, growth and turnaround environments. He had held executive roles in large multinational corporations and startups, including CFO Byton, Electric Last Miles Inc., Ford China and Changan Ford, Head of China Bombardier Aerospace, and CEO Ford Taiwan. Albert worked in Canada, Japan, Thailand, China and Taiwan. His achievements include public listing of Electric Last Mile Inc,, significant fund raises for Byton, successful launches of Ford Nanjing Assembly Plant and vehicle programs, financial led in Ford’s successful acquisition of Land Rover and spinoff of Visteon Automotive Components.

He holds a bachelor’s degree in mechanical engineering and an MBA from the University of Toronto. 

 

NEWS AND TIMELINE

A decade of building something that matters

NOV 2025

Phosphatase Profiling Added to KinSight. We expanded our selectivity profiling services beyond kinases to include phosphatases — giving drug discovery teams a single, trusted partner for characterizing both sides of the phosphorylation equation.

JULY 2025

First Lysate Assays Launched. We introduced our functional activity assays for ERK1/2, AKT1/2/3, and GSK3A/B which allow researchers to quantify kinase activity in cell and tissue lysates. 

JUNE 2025

AsedaSciences and AssayQuant Partner to Advance Kinome-Based Efficacy and Toxicity Insights Earlier in Drug Discovery (press release). 

AUG 2024

Direct to Phase II SBIR proposal approved by the National Cancer Institute (NCI) of the National Institutes of Health (NIH)
(Project Title: Activity-based Sensor Peptides for Direct, High-throughput, and Kinetic Quantitation of Oncogenic Protein Kinases in Unfractionated Cell and Tissue Samples)

MARCH 2024

Future Labs Capital Announces Additional Investment in AssayQuant Technologies, Inc (press release).

JUNE 2023

Kinetic insights with AssayQuant's fully automated KinSight™ Kinome Profiling Services (press release).

JUNE 2023

AssayQuant launches KinSight™ Quantitative Profiling Services.

FEBRUARY 2023

AssayQuant Expands Panel for Kinome Profiling Services (press release).

JANUARY 2023

AssayQuant to present at Biotech Showcase™ 2023 (press release).

AUGUST 2022

AssaQuant partners with Vibliome Therapeutics to establish a Collaborative, Kinetic Relationship (press release).

SEPTEMBER 2021

AssayQuant reaches 375 validated PhosphoSens kinase, phosphatase and lipid kinase (DGK) assays in their product catalog.

MAY 2021

AssayQuant closes Series A Funding.

OCTOBER 2020

Patent granted for "Kinase and/or Phosphatase Sensing via Hydroxyquinoline-Sensitized Chelates," patent exclusively licensed from MIT to AssayQuant Technologies, Inc.

JANUARY 2019

AssayQuant completes 1st 254 validated PhosphoSens assays.

JANUARY 2018

AssayQuant partners with Carna Biosciences to distribute PhosphoSens assay products and services in Japan.

MAY 2016

AssayQuant partners with 21st Century Biochemicals, Inc.

JULY 2015

AssayQuant Technologies, Inc., founded by Drs. Barbara Imperiali (CTO) & Erik Schaefer (President & CSO).

WHY IT MATTERS

Better assays lead to better drugs

Drug discovery is expensive, slow, and uncertain — and a lot of that uncertainty comes from tools that don't give researchers the full picture. Endpoint assays can miss important kinetic information. Indirect detection methods introduce artifacts. And when you’re making decisions about which compounds to advance, ambiguous data is costly.

AssayQuant exists to close that gap. By giving researchers a direct, real-time view of enzyme activity, we help them move through early discovery with more confidence — fewer wasted experiments, fewer compounds that fail late, and a clearer path from hit to lead.

We work with academic labs, biotech startups, and major pharmaceutical companies. What they all have in common is a need for data they can trust. That’s what we’re here to provide.

Stay Informed

Want to hear the latest about our technology? Be among the first to learn about our latest products and services.