AQT0641 PhosphoSens® Serine/threonine Kinase Substrate

A PhosphoSens® serine/threonine kinase substrate validated for 6 kinases, including GRK2, GRK3, GRK4. Continuous, direct, real-time activity measurement — no antibodies, no coupling enzymes, no radioactivity.

See all 6 validated kinases
Catalog number
AQT0641
Enzyme class
Kinase
Residue specificity
Serine/threonine
Validated kinases
6
Assay formats
Kinetic · 6 Red · 4
Kinase families
1

Kinases validated with AQT0641

Every kinase below has a validated PhosphoSens® assay using AQT0641. Select a target to see its kits, recombinant enzyme, pricing and protocols.

KinaseTypeFamilyFormat with AQT0641Link
GRK2 Wild-type GRK Kinetic View assay →
GRK3 Wild-type GRK Kinetic View assay →
GRK4 Wild-type GRK KineticRed View assay →
GRK5 Wild-type GRK KineticRed View assay →
GRK6 Wild-type GRK KineticRed View assay →
GRK7 Wild-type GRK KineticRed View assay →

Bulk substrate

AQT0641 PhosphoSens® Kinase Substrate

Bulk substrate for assay development, screening and high-throughput workflows. Kinase assay kits that include AQT0641 are on each target's assay page.

Price: $2795 USD

How PhosphoSens® substrates work

PhosphoSens® substrates are peptides carrying an environment-sensitive fluorophore next to the phospho-acceptor residue. When the kinase transfers a phosphate to the substrate, fluorescence increases, so activity is read continuously and directly in a plate reader.

  • Real-time progress curves, not single end-points
  • Run at physiologically relevant ATP concentrations
  • No antibodies, coupling enzymes, wash steps or radioactivity
  • One substrate across 6 kinases simplifies selectivity and panel work
Learn about PhosphoSens® technology →

Frequently asked questions

Which kinases is AQT0641 validated for?

AQT0641 is validated for 6 kinases, including GRK2, GRK3, GRK4. See the full list above.

Which PhosphoSens assay formats use AQT0641?

AQT0641 is the PhosphoSens-Kinetic substrate for 6 kinases. It is the PhosphoSens-Red substrate for 4 kinases.

What sizes is AQT0641 available in?

1 mg, 5 mg, 10 mg and 20 mg, priced from $2795 (1 mg) to $37285 (20 mg) USD.

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