PRODUCTS

Kinase & Phosphatase Activity Assays, Substrates, and Reagents for Drug Discovery

Quantify enzyme activity and inhibition in real-time with biochemical fluorescent assays and reagents that support workflows from basic biology to lead optimization across 500+ kinase and phosphatase targets.

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PRODUCT GROUPS

Highly Quantitative Biochemical Fluorescent Assays and Active Recombinant Enzymes

Browse our portfolio of kinase and phosphatase activity assay solutions designed to improve drug discovery with precise, actionable kinetic insights that drive better decision making and success in kinase and phosphatase inhibitor development.

With validated assays for over 500 protein kinases, 35 protein phosphatases, a catalog of 1,100+ highly active enzymes and compound screening and profiling services, we have everything you need to accelerate discovery and development of the next generation of PKIs and PPIs.

500+ Kinase Activity Assays 

Comprehensive kinase assay portfolio offering real-time activity and inhibition measurement with multiple product configurations.

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Phosphatase Activity Assays

Discover continuous, real-time phosphatase activity measurement with a wide selection of assays and customizable reagent options.

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1,000+ Active Enzymes

High-purity recombinant kinases and phosphatases that seamlessly integrate for improved enzyme and inhibitor activity studies. 

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INTRODUCING

Cell Lysate Kinase Assays

Study endogenous kinase activity directly in cell or tissue lysates—no need for cell engineering or overexpression. These assays provide a continuous, real-time readout of phosphorylation in a physiologically relevant context.

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FEATURED PRODUCTS

Featured Products for Drug Discovery and Research

Browse our top-performing assay kits that researchers trust.

EGFR Kinase Activity Substrate Systems

Study enzyme activity, generate kinetic data, discover inhibitors, characterize mechanisms of action (MOA), and more.

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CDC25A Phosphatase Assay Kits

Study enzyme activity, generate kinetic data, discover inhibitors, characterize mechanisms of action (MOA), and more.

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AKT1/2/3 Cell Lysate Kinase Assays

Functional AKT activity readout in a  complex sample for greater confidence in biological impact. 

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PRODUCT RESOURCES

Technical Research and Development Resources for AssayQuant's Enzyme Activity Assays

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 POSTER

Development of a Real-Time, Fluorescence Microplate Assay for Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Activity

Epidermal Growth Factor Receptor (EGFR) wild-type and mutant tyrosine kinase activity and the downstream signaling cascades are pivotal in oncogenesis, drug resistance, and tumor recurrence. Learn how our team developed a continuous, real-time, fluorescence-based assay for EGFR tyrosine kinase inhibitors (TKI’s).

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 POSTER

Sox-based Sensor Phosphopeptides for Continuous, Homogeneous, and Quantitative Monitoring of Protein Phosphatase Activity

Protein phosphatases are critical drug targets for cancer therapy development with a need for robust assays that monitor phosphatase enzyme activity. Learn how our assays continuously monitor protein phosphatase activity.

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