Development of a Covalent Inhibitor of c-Jun N-Terminal Protein Kinase (JNK) 2/3 with Selectivity over JNK1

Lu W, Liu Y, Gao Y, … Gray NS · J Med Chem 2023 · J Med Chem 66(5):3356-3371

JNK1-JNK3 Ser/Thr kinase Covalent inhibitor kineticsInhibitor discovery & SARSelectivity & kinome profiling PhosphoSens