AQT0737 PhosphoSens® Phosphatase Substrate

A PhosphoSens® phosphatase substrate validated for 19 phosphatases (18 wild-type, 1 mutant), including PTPN11, ACP3, ALPI. Continuous, direct, real-time activity measurement — no antibodies, no coupling enzymes, no radioactivity.

Catalog number
AQT0737
Enzyme class
Phosphatase
Validated phosphatases
19
Assay formats
Kinetic · 19
Phosphatase families
6

Phosphatases validated with AQT0737

Every phosphatase below has a validated PhosphoSens® assay using AQT0737. Select a target to see its kits, recombinant enzyme, pricing and protocols.

PhosphataseTypeFamilyFormat with AQT0737Link
ACP3 Wild-type ACP (acid phosphatase) Kinetic View assay →
ALPI Wild-type ALPI (alkaline phosphatase) Kinetic View assay →
DUSP10 Wild-type DUSP (dual-specificity phosphatase) Kinetic View assay →
DUSP14 Wild-type DUSP (dual-specificity phosphatase) Kinetic View assay →
DUSP22 Wild-type DUSP (dual-specificity phosphatase) Kinetic View assay →
EYA4 Wild-type EYA (Eyes Absent family) Kinetic View assay →
PTPN11 Wild-type PTPN (non-receptor PTP) Kinetic View assay →
PTPN11 [T253M/Q257L] Mutant PTPN (non-receptor PTP) Kinetic View assay →
PTPN12 Wild-type PTPN (non-receptor PTP) Kinetic View assay →
PTPN13 Wild-type PTPN (non-receptor PTP) Kinetic View assay →
PTPN22 Wild-type PTPN (non-receptor PTP) Kinetic View assay →
PTPN4 Wild-type PTPN (non-receptor PTP) Kinetic View assay →
PTPN6 Wild-type PTPN (non-receptor PTP) Kinetic View assay →
PTPN9 Wild-type PTPN (non-receptor PTP) Kinetic View assay →
PTPRF Wild-type PTPR (receptor-type PTP) Kinetic View assay →
PTPRJ Wild-type PTPR (receptor-type PTP) Kinetic View assay →
PTPRM Wild-type PTPR (receptor-type PTP) Kinetic View assay →
PTPRQ Wild-type PTPR (receptor-type PTP) Kinetic View assay →
PTPRS Wild-type PTPR (receptor-type PTP) Kinetic View assay →

Bulk substrate

AQT0737 PhosphoSens® Phosphatase Substrate

Bulk substrate for assay development, screening and high-throughput workflows. Phosphatase assay kits that include AQT0737 are on each target's assay page.

Price: $2895 USD

How PhosphoSens® substrates work

PhosphoSens® substrates are peptides carrying an environment-sensitive fluorophore next to the phospho-acceptor residue. When the phosphatase removes the phosphate, fluorescence decreases, so activity is read continuously and directly in a plate reader.

  • Real-time progress curves, not single end-points
  • No antibodies, coupling enzymes, wash steps or radioactivity
  • One substrate across 19 phosphatases simplifies selectivity and panel work
Learn about PhosphoSens® technology →

Frequently asked questions

Which phosphatases is AQT0737 validated for?

AQT0737 is validated for 19 phosphatases (18 wild-type and 1 mutant), including PTPN11, ACP3, ALPI. See the full list above.

Which PhosphoSens assay formats use AQT0737?

AQT0737 is the PhosphoSens-Kinetic substrate for 19 phosphatases.

What sizes is AQT0737 available in?

1 mg, 5 mg, 10 mg and 20 mg, priced from $2895 (1 mg) to $38625 (20 mg) USD.

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