Real-Time Solutions to Accelerate Kinase and Phosphatase Drug Discovery
AssayQuant empowers kinase and phosphatase research with continuous kinetic data, supporting your drug discovery programs in your lab or ours.
Supporting Every Phase of Preclinical Drug Discovery
From early screening through preclinical testing, AssayQuant’s PhosphoSens® Technology and KinSight™ Services platforms accelerate drug discovery by turning kinetic insight into confident, data-driven decisions.
Two Fit-for-Purpose Formats
Choose continuous (FI) for real-time kinetic insight or time-resolved (TRF) for screening applications.
Broad Sample Compatibility
Measure activity in recombinant enzyme systems or complex cell/tissue lysates.
Target
Validation
Confirm kinase and phosphatase targets driving key pathways.
High Throughput Screening
Screen compounds librraies using TRF readouts.
Lead
Identification
Characterize true inhibition and potency from kinetic data.
Lead
Optimization
Differentiate reversible vs. covalent inhibition and refine selectivity.
Preclinical
Testing
Evaluate activity and selectivity in cell or tissue lysates.
A Breakthrough Platform for Continuous Enzyme Activity Measurement
PhosphoSens is AssayQuant’s core technology platform that uses fluorescent sensor peptide substrates to track enzyme activity in real-time. Unlike traditional endpoint assays that only show a single measurement after stopping the reaction, PhosphoSens generates a progress curve in every well — giving you insight into reaction dynamics, inhibitor mechanism, and enzyme behaviour.
Gain a Competitive Edge with Real-Time Phosphorylation Dynamics
Characterizing targets and assessing compound potency, selectivity, and mechanism of action are critical steps in disease research and drug discovery/development, especially with the expanding focus on kinase inhibitors.
Leverage AssayQuant’s PhosphoSens® Technology to gain real-time insights into enzyme activity and inhibition. Our continuous assays simplify workflows, reduce variability, and deliver the data you need to make confident decisions.
Highly Quantitative Biochemical Fluorescent Assays and Active Recombinant Enzymes
AssayQuant’s patented PhosphoSens® Technology forms the basis of its extensive portfolio of over 700 unique enzyme and inhibitor assays.
Our Kinase and Phosphatase Substrates, built on this proprietary platform, are available in configurations tailored for various throughput requirements; from evaluating the technology through high-throughput screens.
Browse our portfolio of kinase and phosphatase activity assay solutions designed to improve drug discovery with precise, actionable kinetic insights that drive better decision making and success in kinase and phosphatase inhibitor development.
With validated assays for over 500 protein kinases, 35 protein phosphatases, a catalog of 1,100+ highly active enzymes and compound screening and profiling services, we have everything you need to accelerate discovery and development of the next generation of PKIs and PPIs.
Explore our range of biochemical kinase & phosphatase activity assay kits, substrates, and supporting reagents designed for flexibility and performance in any lab setting.
Kinase Assays
Comprehensive kinase assay portfolio offering real-time activity and inhibition measurement with multiple product configurations.
Phosphatase Assays
Discover continuous, real-time phosphatase activity measurement with a wide selection of assays and customizable reagent options.
Lysate Assays
A direct, continuous fluorescence system for studying kinase activity and cell signaling in unfractionated lysates and tissue homogenates.
Recombinant Enzymes
Comprehensive selection of kinases and phosphatases designed for a wide range of applications, from basic research to preclinical drug discovery.
Expert Kinase and Phosphatase CRO Services to Advance Your Discovery Programs
KinSight™ delivers kinetic insights into target selectivity, mechanism of action, and inhibitor potency using real-time, continuous activity measurements.
Explore our selectivity profiling, inhibitor characterization and assay development services.
Featured Services
Biochemical Kinase Screening and Profiling Services
Characterize compound selectivity and mechanism of action (MOA) against our panel of 400+ WT protein kinases.
Time-Dependent Inhibition Characterization
Quantify the kinetics behind inhibition with real-time data on inhibitor potency, reversibility, residence time and inactivation kinetics with confidence.
Assay Validation Reports, Detailed Protocols, Guides & Insights
Access our library of protocols, technical guides, and educational materials to support your enzyme research and drug discovery projects & browse expert-written content to help you design, troubleshoot, and optimize kinase and phosphatase assays with confidence.
