ON-DEMAND WEBINAR
Validating the Power of a Continuous Assay Format Using EGFR Inhibitors in Potency, Profiling, and Time-Dependent Inhibition Applications
60 Minutes
Discover how a continuous assay format powers a deep understanding of kinase function. In this webinar, we’ll present data using FDA-approved EGFR inhibitors to demonstrate how our PhosphoSens® assays are used in potency, profiling, and time-dependent inhibition applications to understand compound selectivity and mechanism of action.
Join the webinar and learn:
- How our PhosphoSens fluorogenic sensor peptides power a continuous assay format yielding a progress curve in every well.
- How continuous assays are used to determine binding kinetics and selectivity of your lead compounds, including:
- Reliable and accurate quantification of compound potency
- Superior selectivity assessments and insight into compound-dependent kinetics & MOA with kinome profiling at low or high ATP
- Deep characterization and determination of kinetic parameters for reversible (residence time (τ), IC50 or Ki) or irreversible (kinact, KI, kinact/KI)) inhibitors
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Meet Your Presenters:
Michelle Lyles, PhD, Vice President of Commercial Operations
Michelle has 20+ years of experience in sales/marketing of advanced scientific tools at major life science suppliers. Michelle received her Ph.D. in Biochemistry from Baylor College of Medicine, and post-doctoral training at Emory University and is the author of a dozen publications.
