AssayQuant's compound testing services provide the flexibility to meet your needs, including a variety of compound potency measurements and the option for preincubations, comparison of ATP at the Km app or 1 mM, and analysis with recombinant enzyme or crude cell lysates.
We offer rapid turnaround at seven (7) business days for most determinations, including potency, mechanism of action or residence time and 14 business days for large panel kinome profiling.
PhosphoSens enables complex determinations to provide critical understanding of enzyme inhibitor properties to improve drug performance, including:
13 inhibitors with IC50 values in a 3.4-fold range (1.6 - 5.5nM) are differentiated with kinact/KI.
Jump-dilution method for determination of Residence Time (Tau) for receptor or soluble tyrosine kinases with values ranging from 8.3 min (0/14h) to 1,149 (19.2 h). Due to the high precision of the platform, can detect values from 30 sec to 2 days.